Structural Basis of Infectious and Non-Infectious Amyloids
نویسندگان
چکیده
منابع مشابه
Infectious particles, stress, and induced prion amyloids
Transmissible encephalopathies (TSEs) are believed by many to arise by spontaneous conversion of host prion protein (PrP) into an infectious amyloid (PrP-res, PrP (Sc) ) without nucleic acid. Many TSE agents reside in the environment, with infection controlled by public health measures. These include the disappearance of kuru with the cessation of ritual cannibalism, the dramatic reduction of e...
متن کاملThe Molecular Basis of Procalcitonin Synthesis in Different Infectious and Non-Infectious Acute Conditions
Bacterial infections: By and large PCT levels are elevated in bacterial infections as reported by several studies, but the feature of the response can be different. For example higher peak PCT concentrations are expected in Gram negative as compared to Gram positive infections. Furthermore, differences may also be seen even within the family of Gram negative bacteria: as higher peak PCT concent...
متن کاملA Structural and Functional Comparison Between Infectious and Non-Infectious Autocatalytic Recombinant PrP Conformers
Infectious prions contain a self-propagating, misfolded conformer of the prion protein termed PrPSc. A critical prediction of the protein-only hypothesis is that autocatalytic PrPSc molecules should be infectious. However, some autocatalytic recombinant PrPSc molecules have low or undetectable levels of specific infectivity in bioassays, and the essential determinants of recombinant prion infec...
متن کاملEpidemiology of infectious and non-infectious disease: some comparisons.
At the start, I would like to express my feeling of tremendous honor and pleasure at having been selected by the Council of the Epidemiology Section to deliver the first Wade Hampton Frost lecture. To whatever extent my epidemiological work has been responsible for this, certainly this honor must be shared with my colleagues, many of whom are among you in the audience and with whom I have colla...
متن کاملnon - infectious diseases ?
Disease ecology takes into consideration a broad spectrum of factors comprising the tapestry of a human being's day-today life experience. A disease ecology perspective is one that places human health within the context of a human being's interactions within a wide array of environments. These include the physical environment that surrounds us as well as the social and cultural environments all...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Alzheimer Research
سال: 2008
ISSN: 1567-2050
DOI: 10.2174/156720508784533367